Antivascular endothelial growth factor agents and their development: therapeutic implications in ocular diseases.
Kaiser PK(OH USA)
Amer J Ophthalmol 142(4): 660-8, 2006
・AMDに対する抗VEGF治療の文献考察と臨床治験についての報告。
Pegaptanib (Macugen, OSI/Eyetech, 市販, ITV 6週毎)
Bevacizumab (Avastin, Genentech, Phase?T, ITV)
Ranibizumab (Lucentis, Genentech, Phase?V, ITV 毎月)
Cand5 (—, Acuity, Phase?T/?U, ITV)
Sirna-027 (—, SIRNA Allergen, Phase?T/?U, ITV)
AG-013958 (—, Pfizer, Phase?T/?U, sub tenon)
PTK787 (vatalanib, Novartis, Phase?T, oral毎日)
VEGF Trap (—, Regeneron, Phase?T/?U, ITV)